Interceptor® G2 – Breakthrough To Beat Insecticide Resistance

Interceptor® G2 is a long-lasting, insecticide-treated mosquito net that combats resistant mosquitoes. BASF has received a WHO PQ listing for the Interceptor® G2 net so that it may be used in the fight against malaria. This is the first malaria control product based on a new insecticide class for more than 30 years.


Malaria is preventable and curable. Since 2010, nearly seven million lives, primarily young children, have been saved largely due to the distribution of insecticide- treated mosquito nets. However, growing resistance to public health insecticides could threaten the progress of recent years. Alternatives are urgently needed.


Now, after a collaboration with the Innovative Vector Control Consortium and the London School of Hygiene & Tropical Medicine that lasted more than a decade, BASF’s scientists have successfully repurposed chlorfenapyr – a completely new insecticide class for mosquito control in public health - to be effective on mosquito nets and meet the stringent WHO performance thresholds for public health.


The new net is based on a novel combination of chlorfenapyr and alpha-cypermethrin to both protect sleepers and combat resistant mosquitoes. It is now the first insecticide-treated mosquito net that is not only based on pyrethroid chemistry.


Following the WHO PQ listing, BASF started preparations to launch Interceptor® G2 for malaria control. Depending on local registration processes, the new mosquito net has been available to health ministries and aid organizations since 2018. A second chlorfenapyr product, an indoor residual spray named Sylando® 240SC to coat interior walls and ceilings, is under evaluation for WHO PQ listing.


The story behind the development

"A new development that actually enables the malaria community to deal with resistant mosquitoes - the first new mode of action product since 30 years in this market"


The scientists and developers behind Interceptor® G2 talk about the challenges, the highs and lows, and what this breakthrough in malaria control means to them personally.


Interceptor® G2 - Why is it so special?


What is insecticide resistance?


How challenging was it to develop?


What does it mean to BASF and the people behind it?


Interceptor® G2 – Proven In Independent Trials

Independent trials in Benin, Burkina Faso, Tanzania and Ivory Coast have proven the efficacy of BASF's new chlorfenapyr products against local insecticide-resistant mosquitoes. Field trial results from the Innovative Vector Control Consortium show that BASF’s innovative long-lasting mosquito net, Interceptor® G2, controls insecticide-resistant mosquitoes effectively. The development marks a significant scientific breakthrough that can meet the challenge of malaria control in areas where conventional nets are failing due to resistance.

Interceptor® G2 is the first long-lasting insecticide-treated  net (LN) containing the active ingredient chlorfenapyr in combination with alpha-cypermethrin. Chlorfenapyr is new to vector control and is the first non-pyrethroid adulticide employed on an LN. Due to its new mode of action, chlorfenapyr shows no cross resistance to other insecticide classes.
BASF Product Information


BASF Product Leaflet Interceptor® G2
BASF Product Leaflet

Interceptor® G2

BASF Editorial 'Beating the threat of increasing insecticide resistance
BASF Editorial

Beating the threat of increasing insecticide resistance

Scientific Research Papers And Field Trial Reports On Interceptor® G2