Agriculture

Axalion® Active: A Novel Insecticide Active Ingredient with a New Mode of Action for Piercing and Sucking Insects 

Redefining Modern Pest Control: Axalion® Active is an innovative insecticide active ingredient from BASF designed to help growers effectively control target insects and produce high-quality crops while addressing the evolving needs of modern agriculture. As the first representative of a new class of chemistry with a novel mode of action, Axalion helps farmers protect crop quality through long-lasting control of piercing and sucking pests, including whiteflies and aphids. Based on BASF studies, Axalion has been shown to work harmoniously with beneficial and non-target species when used according to the label instructions. 

As the first representative of a new class of chemistry and IRAC Group 36, Axalion redefines modern pest control by delivering effective, predictable and balanced insect management. With its new mode of action, Axalion controls pests that have developed resistance to existing chemistries, making it an excellent partner for insecticide resistance management and an essential component of Integrated Pest Management (IPM), helping farmers protect crop health, safeguard yield potential and support high-quality production. 

  

Helping Reduce the Spread of Insect-Transmitted Plant Viruses 

Piercing and sucking pests cause significant economic loss in production systems worldwide. In addition to the direct damage they cause, many of these pests also transmit bacteria or viruses, which produce significant plant damage and yield loss. Axalion has been shown to effectively reduce the spread of certain insect pest-vectored bacteria and viruses through rapid pest feeding cessation. This means that even when live insects remain visible after application, growers can be confident that Axalion has already done its job, since insects stop feeding only a few hours after exposure. Feeding cessation ultimately leads to insect mortality. 

Assorted fresh vegetables and fruits

Key Facts about Axalion® Active

  • Novel insecticide active ingredient developed by BASF: dimpropyridaz. 

  • Represents a new class of chemistry: Pyridazine pyrazolecarboxamides (Pyridazine amides). 

  • Features a novel mode of action for piercing and sucking pests, with no known cross-resistance. 

  • Provides effective control of key pests, including aphids, whiteflies, psyllids, scales and leafhoppers. 

  • Delivers superior whitefly control across multiple pest life stages. 

  • Offers long-lasting protection and systemic activity that helps safeguard plant growth.  

  • Based on BASF studies, Axalion has been shown to work harmoniously with beneficial and non-target species when used according to the label instructions. 

  • Can be incorporated into Integrated Pest Management (IPM) programs. 

An Insecticide Tailored to Meet Farmers’ Needs

Uses for Axalion include fruits, vegetables, potatoes, legumes, soybeans, corn, cotton, cereals, beets, oilseed rape and ornamentals.   

To date, two formulations featuring Axalion are set to be available to support farmers:  

  • Efficon® Insecticide, powered by Axalion, will help manage farmers’ most problematic piercing and sucking pests across registered regions and on a broad range of crops.  

  • Durilon® Insecticide, powered by Axalion, is designed to safeguard field crops such as cereals, oilseeds and beets from piercing and sucking pests in selected countries in Europe. 

Discover the Proven Performance of Axalion® Active

Green peach aphid control on spinach

Source: BASF internal trial, 2022.

Treated spinach with Axalion® Active at 60 g ai/ha. 

Silverleaf whitefly control on eggplant

Source: BASF internal trial, 2022.

Treated eggplant with Axalion® Active at 120 g ai/ha. 

Key Features and Benefits of Axalion® Active Insecticide

Flexibility in timing and application


The systemic properties of Axalion provide growers with a wide application window across early and late crop growth stages. This includes applications in later growth stages, when crop canopies are already closed and reaching target pests would typically be more challenging. Axalion combines excellent solubility with xylem mobility, enabling upward (acropetal) movement within the plant to help protect new growth. It also exhibits translaminar movement from the upper leaf surface to the underside of leaves, supporting coverage where target pests often reside. These systemic properties contribute to long-lasting residual control and help protect both existing and newly developed plant tissues.

Redefining modern pest control  


With Axalion, growers gain access to an innovative insecticide active ingredient that delivers strong efficacy while addressing the evolving needs of modern agriculture. Axalion is designed to provide long-lasting control of piercing and sucking insects while working harmoniously with non-target organisms, including beneficial insects and pollinators when used according to label instructions, providing growers with a valuable tool for modern insect management. 

To learn more about why Axalion is redefining modern pest control, click here.

 

The Story Behind the New Innovation to Control Piercing & Sucking Pests

Axalion® Active Insecticide: A New Mode of Action

How Does Axalion® Active Work? 

Axalion introduces a new class of chemistry and a novel mode of action for the control of piercing and sucking pests. Based on BASF research and discovery, it is the sole representative of Insecticide Resistance Action Committee (IRAC) Group 36 and targets a unique site within insect chordotonal organs. 

Chordotonal organs are specialized sensory structures that help insects perceive movement, orientation, balance and environmental signals that are essential for survival. By disrupting the function of these organs through a novel target site, Axalion provides effective, long-lasting control of key pests, including whiteflies and aphids.  

As the only member of the Pyridazine Pyrazolecarboxamide (Pyridazine amide) class, Axalion offers growers a differentiated tool for modern insect management. Its unique mode of action helps diversify insect control programs, supports resistance management strategies and reduces reliance on existing insecticide chemistries while maintaining strong efficacy against economically important piercing and sucking pests. 
 

How Does Axalion® Active Support Integrated Pest Management?

Integrated Pest Management (IPM) combines biological, cultural, mechanical and chemical measures to manage pest populations over the long term. Axalion contributes to IPM by providing a novel mode of action that can be integrated into resistance management programs and incorporated into broader IPM programs alongside biological insecticides or other pest management strategies, helping preserve the effectiveness of insecticides over time. 

Axalion® Active At-a-Glance

Broad spectrum control of piercing and sucking insects 
•  Whiteflies
•  Aphids
•  Leafhoppers/jassids 
•  Thrips
•  Scales
•  Mealybugs
•  Psyllids
Axalion® Active’s scope includes more than 150 crops worldwide 
•  Fruits
•  Vegetables
•  Soybeans
•  Cotton
•  Cereals
•  Beets
•  Oilseed rape
•  Ornamentals
Application methods
•   Greenhouse
•   Foliar spray
•   Drench and drip
•   Drone

Axalion® Active FAQs

What is IRAC Group 36?

IRAC Group 36 is a unique insecticide mode of action classification established by the Insecticide Resistance Action Committee (IRAC). Axalion® Active is the sole representative of this group and the first new mode of action classification for the control of piercing and sucking pests since 2015. Axalion® Active targets a previously unexploited site within the insect's chordotonal organs, disrupting essential sensory functions such as orientation and coordination. As a result, target pests quickly become unable to feed and eventually die. 
This novel mode of action provides growers with a powerful new tool to control difficult pest populations while supporting long-term resistance management programs. 

 

How does Axalion® Active support resistance management?

Axalion® Active supports resistance management through its novel IRAC Group 36 mode of action, which is distinct from existing insecticide chemistries and has no known cross-resistance with currently available solutions. This allows growers to effectively manage pest populations that may have developed resistance to other insecticides. 
As an effective rotation partner within Integrated Pest Management (IPM) and Insecticide Resistance Management (IRM) programs, Axalion® Active helps preserve the effectiveness of existing pest control tools while delivering reliable performance against key piercing and sucking pests.

How does Axalion® Active differ from conventional insecticides?

Axalion® Active’s novel IRAC Group 36 mode of action quickly stops pest feeding, helping protect crops from damage and reducing the spread of insect-vectored viruses. Combined with systemic movement, long-lasting residual activity and effectiveness against resistant pest populations, Axalion delivers the predictable, balanced performance needed for modern pest management programs. In BASF studies, Axalion also has been shown to work harmoniously with non-target organisms, including beneficial insect and pollinator species when used according to label instructions, and it has been assessed and authorized by the competent regulatory authorities in the countries where it is registered. 

Disclaimer

Use plant protection products safely. Always read the label and product information before use.

Axalion® is a registered trademark of BASF. ©2026 BASF. All Rights Reserved.

Performance based on best BASF internal regulatory knowledge and research.  Axalion regulatory profile was confirmed by authorities in Australia, Mexico and Brazil. Axalion poses low risk to human health when used according to label instructions.

Availability of key active ingredients, products and mixtures vary by region. Regulatory requirements vary among countries and their regulatory authorities. Check with your local BASF representative regarding the use of products in your region.

Related topics

Redefining Modern Pest Control 
Axalion® Active meets the highest regulatory standards for modern crop protection while delivering excellent efficacy and resistance management.
How insecticides can work with beneficial insects
Learn how insecticides like Axalion can be developed to work in combination with beneficial insects used by growers to protect food crops.