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    Urban & Rural Pest Control Beating insecticide resistance

    Interceptor® G2 – breakthrough to beat insecticide resistance

    BASF has received the historic recommendation from the World Health Organization (WHO) that Interceptor® G2 may now be used in the fight against malaria. Interceptor® G2 is a long-lasting, insecticide-treated mosquito net that combats resistant mosquitoes. This is the first WHO recommendation for a product based on a new insecticide class in more than 30 years.

    Malaria is preventable and curable. Since 2010, nearly seven million lives, primarily young children, have been saved largely due to the distribution of insecticide- treated mosquito nets. However, growing resistance to public health insecticides could threaten the progress of recent years. Alternatives are urgently needed.

    Now, after a collaboration with the Innovative Vector Control Consortium and the London School of Hygiene & Tropical Medicine that lasted more than a decade, BASF’s scientists have successfully repurposed chlorfenapyr – a completely new insecticide class for mosquito control in public health - to be effective on mosquito nets and meet the stringent WHO performance thresholds for public health.

    The new net is based on a novel combination of chlorfenapyr and alpha-cypermethrin to both protect sleepers and combat resistant mosquitoes. It is now the first WHO-recommended insecticide-treated mosquito net that is not only based on pyrethroid chemistry.

    Following the WHO recommendation, BASF can now start preparations to launch Interceptor® G2 for malaria control. Depending on local registration processes, the new mosquito net is expected to be available to health ministries and aid organizations starting from the beginning of 2018. A second chlorfenapyr product, an indoor residual spray named Sylando® 240SC to coat interior walls and ceilings, is in the process of WHO evaluation.

    The story behind the development

    "A new development that actually enables the malaria community to deal with resistant mosquitoes - the first new mode of action product since 30 years in this market"

    The scientists and developers behind Interceptor® G2 talk about the challenges, the highs and lows, and what this breakthrough in malaria control means to them personally.

    Interceptor® G2 – proven in independent trials

    Independent trials in Benin, Burkina Faso, Tanzania and Ivory Coast have proven the efficacy of BASF's new chlorfenapyr products against local insecticide-resistant mosquitoes. Field trial results from the Innovative Vector Control Consortium show that BASF’s innovative long-lasting mosquito net, Interceptor® G2, controls insecticide-resistant mosquitoes effectively. The development marks a significant scientific breakthrough that can meet the challenge of malaria control in areas where conventional nets are failing due to resistance.

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